Terapi Tissue Plasminogen Activator untuk Stroke Iskemik Akut
نویسندگان
چکیده
Prevalensi stroke terus meningkat setiap tahun. Penanganan kasus harus dilakukan sesegera mungkin untuk memaksimalkan pemulihan serta mencegah berulang. Pada iskemik akut, pengobatan fibrinolitik tPA terbukti efektif. Beberapa kriteria pemberian dipenuhi. Pasien yang mendapat observasi tekanan darah ketat dan memastikan tidak terjadi efek samping perdarahan. Hingga saat ini, hanya alteplase disetujui pada pasien akut. Telaah ilmiah berbasis bukti menunjukkan manfaat lain. yaitu tenecteplase.
 The prevalence of continues to increase. To minimize brain injury, prompt management is necessary maximize patient recovery and prevent recurrent strokes. Fibrinolytic has been proven be effective for acute ischemic stroke. Several criteria must met before administration. Patients should receive close monitoring blood pressure bleeding risk. Until recently, only approved fibrinolytic treatment in evidence-based studies have shown the benefits tenecteplase - another management.
منابع مشابه
The Outcome of Treatment With Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke
Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...
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The use of intravenous tissue plasminogen activator (tPA) in the treatment of ischemic stroke is limited by its propensity to exacerbate brain edema and hemorrhage. The mechanisms underlying these deleterious effects of tPA remain incompletely understood. The purpose of this study was to delineate a pathway of tPA-mediated complement cascade activation in stroke and to determine whether complem...
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ژورنال
عنوان ژورنال: Cermin Dunia Kedokteran
سال: 2023
ISSN: ['0125-913X', '2503-2720']
DOI: https://doi.org/10.55175/cdk.v50i3.661